| SKU: | A10605-100ul |
| Category: | Antibodies |
| Aliases: | CD106 ; MGC99561 ; INCAM-100 ; DKFZp779G2333 ; VCAM1 |
| Product Type: | Monoclonal Antibody |
| UnitprotID: | P19320 |
| Immunogen Species: | Human |
| Immunogen: | Purified recombinant fragment of human VCAM1 expressed in E. Coli |
| Host Species: | Rabbit |
| Species Reactivity: | Human |
| Applications: | ELISA , WB , IHC |
| Dilution: | WB:1:500-1:5000 , IHC:1:50-1:500 |
| Clonality: | Monoclonal |
| Isotype: | IgG1 |
| Conjugate: | Non-conjugated |
| Buffer: | Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Form: | Liquid |
| Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Research Areas: | Neuroscience；Cancer；Cardiovascular ; Signal transduction ；Stem cells |
| Background: | This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells. |
