Purified recombinant fragment of human VCAM1 expressed in E. Coli
ELISA , WB , IHC
WB:1:500-1:5000 , IHC:1:50-1:500
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Neuroscience；Cancer；Cardiovascular ; Signal transduction ；Stem cells
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells, myeloid cells, and endothelial cells.