ZNF423 Antibody, Biotin conjugated

$190.00

SKUStock Size PriceQuantity
A38956-100ul Available 100ul $299.00
spinner
A38956-50ul Available 50ul $190.00
spinner
Request COA

Product Information

SKU:A38956
Category:
Aliases: Zinc finger protein 423 (Olf1/EBF-associated zinc finger protein) (hOAZ) (Smad- and Olf-interacting zinc finger protein), ZNF423, KIAA0760 NPHP14 OAZ
Product Type: Polyclonal Antibody
UnitprotID: Q2M1K9
Immunogen Species: Homo sapiens (Human)
Immunogen: Peptide sequence from Human Zinc finger protein 423 protein (39-57AA)
Host Species: Rabbit
Species Reactivity: Human
Applications: ELISA
Clonality: Polyclonal
Isotype: IgG
Conjugate: Biotin
Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form: Liquid
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Purification Method: Antigen Affinity Purified
Target Names: ZNF423
Research Areas: Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction
Background: Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation.