ZNF423 Antibody, HRP conjugated
$190.00
SKU | Stock | Size | Price | Quantity | ||
---|---|---|---|---|---|---|
A38954-100ul | Available | 100ul | $299.00 | |||
A38954-50ul | Available | 50ul | $190.00 |
Product Information
SKU: | A38954 |
Category: | Antibodies |
Aliases: | Zinc finger protein 423 (Olf1/EBF-associated zinc finger protein) (hOAZ) (Smad- and Olf-interacting zinc finger protein), ZNF423, KIAA0760 NPHP14 OAZ |
Product Type: | Polyclonal Antibody |
UnitprotID: | Q2M1K9 |
Immunogen Species: | Homo sapiens (Human) |
Immunogen: | Peptide sequence from Human Zinc finger protein 423 protein (39-57AA) |
Host Species: | Rabbit |
Species Reactivity: | Human |
Applications: | ELISA |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | HRP |
Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Form: | Liquid |
Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Purification Method: | Antigen Affinity Purified |
Target Names: | ZNF423 |
Research Areas: | Epigenetics and Nuclear Signaling; Neuroscience; Signal transduction |
Background: | Transcription factor that can both act as an activator or a repressor depending on the context. Plays a central role in BMP signaling and olfactory neurogenesis. Associates with SMADs in response to BMP2 leading to activate transcription of BMP target genes. Acts as a transcriptional repressor via its interaction with EBF1, a transcription factor involved in terminal olfactory receptor neurons differentiation; this interaction preventing EBF1 to bind DNA and activate olfactory-specific genes. Involved in olfactory neurogenesis by participating in a developmental switch that regulates the transition from differentiation to maturation in olfactory receptor neurons. Controls proliferation and differentiation of neural precursors in cerebellar vermis formation. |